
Discover everything you need to know about the best Silent Builds in Slay the Spire 2, including the best relics and core cards.
The Silent is a fast, tactical assassin‑style hero who specializes in debuffs, combo attacks, and discard synergies. The playstyle of this character is combo‑focused and strategic in Slay the Spire 2. Many builds aim to combo multiple card effects together in a single turn.
She has multiple viable archetypes, allowing the players to adapt based on cards or relics. The Poison build applies Poison stacks to enemies, while the Shiv build plays lots of zero‑energy Shiv cards.
How the Silent Works

Silent is a stealthy, high‑skill rogue in Slay the Spire 2 that focuses on quick strikes and manipulating cards during combat. It comes with a starting health of 70 HP and has a Starting Relic (Ring of the Snake). This relic allows Silent to draw additional cards at the start of combat to gain high tempo. It can deal damage to enemies with small attacks and stack poison.
The Silent has three distinct, unique mechanics that make her different and devastating from other characters like Regent and Necrobinder. Playing this archetype requires good sequencing, timing, and deck synergy.
The Sly Discard Engine allows you to use discard outlets and lots of Sly cards. The Poison Deck can stack poison on the enemies to defeat them over time. The Silent generate multiple shivs, buff them, and overwhelm foes for Shiv Swarm. If you’re looking for a character with an excellent damage potential in the late game, then this is your best choice. This character is difficult to play and has no healing system in the game.
Sly

The Sly are the cards with the Sly keyword that automatically play for free in Slay the Spire 2. This allows you to flip multiple discards into a huge advantage to play many cards in the same turn. The Silent decks are centered around building up a hand of Sly cards to trigger them through discard outlets for explosive turns.
Poison
This character can stack poison on the enemies at the start of the combat to deal massive damage over time. Haze, Envenom, and Noxious Fumes are the best cards to choose for this mechanic. Poison effect increases over time and pairs with the defensive playstyle.
Shivs
Generate multiple Shivs using the cards like Blade Dance and Storm of Steel in Slay the Spire 2. Shivs can hit very hard due to buffs like Accuracy. They also work together with effects that trigger when playing cards. Creating some specific cards allows you to enable certain relics for The Silent.
Best Shiv Deck Build

The Shive Deck build in Slay the Spire 2 focuses on generating multiple Shivs, buffing the damage, playing many cards in a turn, and using low‑cost cards. These are the exhaust attack cards that come from other cards and relics. Cards like Blade Dance, Cloak and Dagger, Infinite Blades, and Leading Strike are the best cards to add Shivs to your hand to spam them.
Other cards like Accuracy, After Image, Envenom, and Finisher make your Shiv attack deck stronger. Choosing the best relics like Ninja Scroll, Shuriken, Kunai, Ornamental Fan, and Nunchaku is crucial to make the Shiv deck more powerful. I recommend playing Blade Dance and Cloak and Dagger whenever possible. You can also pick Accuracy early and grab After Image for Shiv damage and defense.
Best Common and Uncommon Cards
Choose the best Common and Uncommon cards for the Shiv Deck build that adds more Shivs into your hand in Slay the Spire 2.
| Card | Card Type | Effect |
| Blade Dance | Common Card | Add 3 Shivs into your hand. |
| Cloak and Dagger | Common Card | Gain Block and add 1 Shiv into your hand. |
| Leading Strike | Common Card | Adds a Shiv into your hand and deals 7 damage. |
| Accuracy | Uncommon Card | Increases the damage (4) of all your Shivs. |
| Infinite Blades | Uncommon Card | Add a Shiv to your hand at the start of each turn. |
| Finisher | Uncommon Card | Deals additional damage (6) based on how many attacks you played this turn. |
Best Core Cards

Choose the core cards that generate Shivs and turn them into huge damage or defense for the Shiv Deck build in Slay the Spire 2.
| Card | Effect |
| After Image | Grants Block for every card played. |
| Knife Trap | Play every Shiv in your Exhaust Pile on the enemy. |
| Fan of Knives | Shivs now hit all enemies and add 4 Shivs to your hand. |
| Serpent Form | Deal 4 damage to a random enemy whenever you play a card. |
| Hidden Daggers | Discard 2 cards and add 2 Shivs into your hand. |
Best Relics For Shiv Deck Build
Prefer using the relics for the Shiv Deck build that make your Shiv strategy strong to dominate enemies in combat. Here are the best relics to choose for this build in Slay the Spire 2.
| Relic | Effect |
| Helical Dart | Gain 1 Dexterity for a turn whenever you play a Shiv. |
| Ninja Scroll | Initiate the fight with 3 Shivs in hand. |
| Kunai | Gain 1 Dexterity every time you play 3 attacks in a single turn. |
Best Poison Deck Build

The Poison Deck build in Slay the Spire 2 focuses on applying Poison stacks that damage enemies automatically at the start of their turns. This allows you to focus on defense while the Poison chips away at elite enemies. Make sure to pick poison-based cards like Poison Stab, Deadly Poison, Noxious Fumes, Haze, and more for this build.
The best relics like Snecko Skull, Unsettling Lamp, Twisted Funnel, and The Specimen focus on adding extra poison to the enemies. The damage becomes more after you’ve had enough Poison and scaling cards. Use block and defensive cards in the early game, as the Poison doesn’t help you survive the battle.
Best Common and Uncommon Cards
Choose the cards that focus on applying Poison stacks repeatedly and then scaling them to deal massive damage over time in combat. Use Deadly Poison and Poisoned Stab in the beginning, and then follow up with the Noxious Fumes.
| Card | Card Type | Effect |
| Deadly Poison | Common Card | Apply 5 Poison to an enemy. |
| Poisoned Stab | Common Card | Deal 6 damage and apply 3 Poison. |
| Noxious Fumes | Uncommon Card | At the start of your turn, apply 2 Poison to all enemies. |
| Catalyst | Uncommon Card | Doubles an enemy’s Poison. |
| Outbreak | Uncommon Card | Every 3 times you play Poison, deal 11 damage to all enemies. |
Best Core Cards

Prefer using the best poison-based cards for Act 2 or Act 3 that multiply or trigger Poison for big damage. Here are the best core cards for the Poison Deck build in Slay the Spire 2.
| Card | Effect |
| Accelerant | Poison is triggered one additional time. |
| Bubble Bubble | Applies a lot of Poison if the enemy already has some. |
| Mirage | Gain Block equal to Poison on all enemies. |
| Burst | Your next Skill is played an extra time this turn. |
| Haze | Allows you to apply 4 Poison to all enemies. |
Best Relics for Poison Deck Build
Choose the relics that amplify Poison, apply Poison for free, or transfer Poison between enemies in combat while running this build in Slay the Spire 2.
| Relic | Effect |
| Snecko Skull | Apply +1 additional Poison whenever you apply Poison. |
| Twisted Funnel | Add a set amount of Poison to all enemies at the beginning of the fight. |
| The Specimen | Transfer the Poison to another enemy when an enemy with Poison dies. |
Sly Deck Build

The Sky Deck is a discard‑powered archetype that allows you to automatically play for free when a card is discarded. This setup transforms into your main resource, letting you chain several cards without needing to use Energy. Fill your hand with Sly cards and use discard outlets to discard your hand in combat.
The objective of the Sky Deck is to chain multiple card effects while cycling through your deck and keep triggering Sly effects. Sly cards can have damage effects like Ricochet, Dagger Throw, Flick‑Flack, and defensive effects like Untouchable. Acrobatics, Calculated Gamble, Dagger Throw, Untouchable, and Ricochet are the best cards to consider for this setup.
Best Common and Uncommon Cards
Choose the best Common and Uncommon cards to trigger Sly effects in combat. Draw engines by cycling discard cards to refill your hand to keep triggering many Sly cards.
| Card | Card Type | Effect |
| Acrobatics | Common Card | Draw 3 cards, then discard 1. |
| Dagger Throw | Common Card | Deal damage, draw 1, discard 1. |
| Flick‑Flack | Common Card | Deal 7 damage to all enemies. |
| Tactician | Uncommon Card | Allows you to gain Energy to do more actions in the same turn. |
| Reflex | Uncommon Card | Draw 2 cards to discard more Sly cards. |
| Speedster | Uncommon Card | Deal 2 damage to all enemies whenever you draw a card during your turn. |
Best Core Cards For Sly Deck Build

Choose the core cards to cycle your deck and fill your hand with Sly cards to discard while running the Sly Deck build in Sly the Spire 2.
| Card | Effect |
| Prepared | Draw 1 and discard 1. |
| Tools of the Trade | Draw 1 card and discard 1 card at the start of your turn. |
| Master Planner | When you play a Skill, it gains Sly. |
| Abrasive | Gain 1 Dexterity and 4 thorns. |
| Serpent Form | Whenever you play a card, deal 4 damage to a random enemy. |
Best Relics for Sly Deck
Prefer using the Relics that reward you for discarding, turning each discard into extra value in Slay the Spire 2.
| Relic | Effect |
| Tingsha | Whenever you discard a card, deal 3 damage. |
| Tough Bandages | Gain 3 Block whenever you discard a card during your turn. |
| Hovering Kite | Gain Energy the first time you discard each turn. |






